Somatic and germline mosaicism in interspecific chimaeras between Mus musculus and Mus caroli
نویسندگان
چکیده
منابع مشابه
Somatic and germline mosaicism in interspecific chimaeras between Mus musculus and Mus caroli.
Detailed analysis of mosaicism in interspecific chimaeras between Mus musculus and Mus caroli revealed that cells of the two species could coexist and interact normally in all tissues studied. No selection occurred against M. caroli cells during gestation of chimaeras in the M. musculus uterus, but some tissue-specific differential growth of M. musculus and M. caroli cells occurred during postn...
متن کاملInterspecific chimeras in mammals: successful production of live chimeras between Mus musculus and Mus caroli.
Live chimeras between two species of mouse, Mus musculus and Mus caroli, were produced by blastocyst injection. These chimeras were entirely similar to M. musculus in equilibrium with M. musculus chimeras in their somatic tissue organization. This is the first report of completely normal development of interspecific chimeras in mammals.
متن کامل"Interspecific Chimeras in Mammals: Successful Production of Live Chimeras Between Mus musculus and Mus caroli" (1980), by Janet Rossant and William I. Frels
In 1980 Janet Rossant [5] and William I. Frels [6] published their paper, ?Interspecific Chimeras in Mammals: Successful Production of Live Chimeras Between Mus musculus and Mus caroli ,? in Science. Their experiment involved the first successful creation of interspecific mammalian chimeras [7]. Mammalian chimeras [8] are valuable for studying early embryonic development. However, in earlier st...
متن کاملSuperovulation and in vitro oocyte maturation in three species of mice (Mus musculus, Mus spretus and Mus spicilegus).
Mouse oocytes can be obtained via superovulation or using in vitro maturation although several factors, including genetic background, may affect response. Our previous studies have identified various mouse species as models to understand the role of sexual selection on the evolution of sperm traits and function. In order to do comparative studies of sperm-oocyte interaction, we sought reliable ...
متن کاملGastrulation in Mus musculus (common house mouse)
As mice embryos develop, they undergo a stage of development called gastrulation [7]. The hallmark of vertebrate gastrulation [7] is the reorganization of the inner cell mass [8] (ICM) into the three germ layers [9]: ectoderm [10], mesoderm [11], and endoderm [12]. Mammalian embryogenesis [13] occurs within organisms; therefore, gastrulation [7] was originally described in species with easily o...
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ژورنال
عنوان ژورنال: Development
سال: 1983
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.73.1.193